Protein Modification Reagents
Medchemexpress LLC Biotin-PEG4-PFP ester | 1334172-58-5 | 96.2% | 657.65 g/mol | C27H36F5N3O8S | 5 MG
Biotin-PEG4-PFP ester is a biotinylated, cleavable PEG-based linker containing a pentafluorophenyl activated ester for efficient coupling to primary amines. It is used in antibody-drug conjugate (ADC) synthesis, PROTAC linker construction, and the biotinylation of proteins or small molecules. The reagent is supplied as a powder and requires low-temperature storage to maintain stability.
- Biotinylated PEG4 spacer with pentafluorophenyl activated ester.
- Suitable for coupling to primary amines in proteins and small molecules.
- Used as an ADC and PROTAC linker or biotinylation reagent.
- High purity and defined storage conditions for stability.
- Available in small milligram quantities for research use.
Medchemexpress LLC Mal-PEG2-oxyamine TFA | 00-00-0 | 96.5% | 358.27 g/mol | C12H17F3N2O7 | 5 MG
Mal-PEG2-oxyamine TFA is a PEG-based PROTAC linker containing a maleimide and an oxyamine (trifluoroacetate salt) joined by a PEG2 spacer. It is designed for orthogonal bioconjugation-maleimide reacts with thiols and oxyamine forms oximes with aldehydes/ketones-making it suitable for assembling PROTACs and other conjugates. The product is supplied as a colorless to light yellow liquid with high purity and good DMSO solubility.
- Enables thiol conjugation via maleimide chemistry.
- Permits oxime ligation through the oxyamine functional group.
- Short PEG2 spacer provides moderate linker flexibility.
- High solubility in DMSO (≈250 mg/mL) for convenient stock solutions.
- High purity (~96.5%) suitable for research synthesis.
- Stable when stored sealed and protected from moisture.
CONJU PROBE LLC DBCO-PEG3-Oxyamine | 25 mg
DBCO-PEG3-Oxyamine | Purity: >95% | Mol Wt: 552.62 | 25 mg
Cayman Chemical dPE-PEG 2000-amInsodIum 10mg
A PEGylated derivative of DSPE; has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents; has been used in the synthesis of fluorescein isothiocyanate-loaded mesoporous silica nanoparticles for imaging applications; can be conjugated to a variety of functional molecules for improved cellular targeting and uptake of DSPE-PEG(2000)-amine-containing nanoparticles
Medchemexpress LLC Pomalidomide-PEG2-acetic acid | 2143097-05-4 | 99.4% | 419.39 | 25 MG
Pomalidomide-PEG2-acetic acid is a conjugate composed of an E3 ligase ligand and a linker. It can be used for PROTAC synthesis.
- Conjugate of an E3 ligase ligand and a linker
- Can be used for PROTAC synthesis
- Appearance: solid, light yellow to yellow
eMolecules 1391914-41-2 | Propargyl-PEG1-SS-alcohol | Broadpharm | MFCD28505558 | 192.290 | C7H12O2S2 | 98.000 | OCCSSCCOCC#C | 1g | 550804207
Propargyl-PEG1-SS-alcohol | Broadpharm | 1391914-41-2 | MFCD28505558 | 192.290 | C7H12O2S2 | 98.000 | OCCSSCCOCC#C | 1g | 550804207
Medchemexpress LLC AgAuSe-PEG-NH2 (1000 nm) | 250 UL
AgAuSe-PEG-NH2 (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm that can be used in bioimaging.
- Emits fluorescence in the near-infrared II region
- Emission peak reaching 1000 nm
- Useful for bioimaging
![eMolecules 5-(Azide-PEG9-ethylcarbamoyl)pentanoic t-butyl ester | Broadpharm |666.810 | C30H58N4O12 | 0.000 | CC(C)(C)OC(=O)CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 50mg | 490840941](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502476874.JPG-250.jpg)
eMolecules 5-(Azide-PEG9-ethylcarbamoyl)pentanoic t-butyl ester | Broadpharm |666.810 | C30H58N4O12 | 0.000 | CC(C)(C)OC(=O)CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 50mg | 490840941
5-(Azide-PEG9-ethylcarbamoyl)pentanoic t-butyl ester | Broadpharm |666.810 | C30H58N4O12 | 0.000 | CC(C)(C)OC(=O)CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 50mg | 490840941
Medchemexpress LLC Methoxy-polyethylene glycol-distearoylphosphatidylethanolamine sodium salt | 95.0% | 3,000 Da (average) | 250 MG
m-PEG-DSPE sodium (MW 3000) is a methoxy-polyethylene glycol-conjugated distearoylphosphatidylethanolamine supplied as the sodium salt for research use. It is used as a PEG lipid in nanoparticle and micelle formulations to extend circulation time, improve colloidal stability, and reduce protein adsorption in colloidal drug-delivery systems.
- PEGylated phospholipid sodium salt for surface modification.
- Average molecular weight ~3,000 Da reflecting PEG chain length.
- Purity approximately 95.0% as specified by the manufacturer.
- Suitable for formulation of liposomes, lipid nanoparticles, and micelles.
- Improves circulation time and reduces opsonization.
- Supplied as a small-scale research package for laboratory use.
Medchemexpress LLC DBCO-PEG4-maleimide | 1480516-75-3 | MFCD22572659 | 95.9% | 674.74 g/mol | C36H42N4O9 | 50 MG
DBCO-PEG4-Maleimide is a DBCO-containing click chemistry reagent and non-cleavable linker used for bioconjugation. It enables rapid strain-promoted alkyne-azide cycloaddition with azide-functionalized molecules and provides a maleimide handle for thiol conjugation, making it suitable for antibody-drug conjugate assembly and other bioconjugation workflows.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups.
- Provides a thiol-reactive maleimide for cysteine conjugation.
- Includes a PEG4 spacer to improve solubility and reduce steric hindrance.
- High purity appropriate for research and conjugation applications.
- Soluble in DMSO and compatible with common in vivo formulations.
- Store protected from light and under recommended temperature conditions to preserve stability.
Medchemexpress LLC Biotin-PEG4-acid | 721431-18-1 | 97.0% | 5 G
Biotin-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTAC. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTAC
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 658858-65-2 | THP-PEG9 | Broadpharm | MFCD29764333 | 454.557 | C21H42O10 | 98.000 | OCCOCCOCCOCCOCCOCCOCCOCCOC1CCCCO1 | 1g | 303671227
THP-PEG9 | Broadpharm | 658858-65-2 | MFCD29764333 | 454.557 | C21H42O10 | 98.000 | OCCOCCOCCOCCOCCOCCOCCOCCOC1CCCCO1 | 1g | 303671227
Sino Biological Anti-MMAE Antibody (Biotin, AVI Tag), Mouse MAb 1 mg
This product is an antibody recombinantly expressed in HEK293 cells, and biotinylated via BirA enzyme.